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CaCCinh-A01
| 产品编号 : |
C13430 |
| 产品名称： |
CaCCinh-A01 |
| 英文名： |
CaCCinh-A01 |
| 别名： |
CaCCinh-A01;CaCC(inh)-A01 |
| 化学名称： |
6-tert-butyl-2-(furan-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid |
| CAS No. ： |
407587-33-1 |
| 结构式 ： |
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| 分子式： |
C18H21NO4S |
| 分子量： |
347.43 |
| 溶解性： |
Soluble in DMSO |
| 纯度： |
HPLC>98% |
| Usage: |
Potent, selective class A inhibitor of calcium-activated chloride channels (CaCCs);An aminothiophene that inhibits Calcium-activated Chloride Channel (CaCC) current influx induced by multiple calcium-elevating agonists (IC50 = 10 μM) without inhibiting calcium elevation, and CaMKII and CFTR activity. Inhibits CaCC chloride response following agonist stimulation in human bronchial and intestinal epithelial cells. Also demonstrates an inhibitory effect on TMEM16A channels (IC50 = 2.1 μM). |
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| 如果该化合物涉及专利保护，请勿作为商业目的使用，且仅供实验分析及研究之目的；如被销售到构成专利侵权的国家，则相应的一切风险将由买方承担。 |
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