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Products - Reference Compounds&Impurities - Anti-Cancer(Oncology) Agents
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(±)-Nutlin-3
Catalogue No. : |
C14553 |
Product Name: |
(±)-Nutlin-3 |
Synonym: |
Nutlin 3;Nutlin3 |
Chemical Name: |
(±)-4-[4,5-bis-(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one |
CAS No. : |
548472-68-0 |
Structure : |
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Molecular Formula: |
C30H30Cl2N4O4 |
Molecular Weight: |
581.5 |
Purity: |
>98% |
Usage: |
Nutlin-3 is MDM2 antagonist. Nutlin-3 inhibits the MDM2-p53 interaction (IC50 = 0.09 μM) and activates p53. Antiproliferative agent;chemotherapeutic agent; induces apoptosis in cancer cells. |
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