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Products - Reference Compounds&Impurities - Anti-Cancer(Oncology) Agents
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AMG 900
| Catalogue No. : |
C16406 |
| Product Name: |
AMG 900 |
| Synonym: |
AMG-900;AMG900 |
| Chemical Name: |
N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine |
| CAS No. : |
945595-80-2 |
| Structure : |
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| Molecular Formula: |
C28H21N7OS |
| Molecular Weight: |
503.58 |
| Purity: |
>98% |
| Usage: |
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM. It is >10-fold selective for Aurora kinases than p38α, Tyk2, JNK2, Met and Tie2. Phase 1.AMG 900 is a novel class of ATP-competitive phthalazinamine small molecule inhibitors of aurora kinases. |
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