Simeprevir(TMC-435350)
| Catalogue No. : |
C16441 |
| Product Name: |
Simeprevir(TMC-435350) |
| Synonym: |
TMC435;TMC435350;TMC-435350;TMC 435 |
| Chemical Name: |
(2R,3aR,10Z,11aS,12aR,14aR)-N-(Cyclopropylsulfonyl)-2,3,3a,4,5,6,7,8,9,11a,12,13,14,14a-tetradecahydro-2-[[7-methoxy-8-methyl-2-[4-(1-methylethyl)-2-thiazolyl]-4-quinolinyl]oxy]-5-methyl-4,14-dioxocyclopenta[c]cyclopropa[g][1,6]diazacyclotetradecine-12a(1H)-carboxamide |
| CAS No. : |
923604-59-5 |
| Structure : |
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| Molecular Formula: |
C38H47N5O7S2 |
| Molecular Weight: |
749.94 |
| Appearance: |
White to off-white solid |
| Purity: |
HPLC>98% |
| Usage: |
Simeprevir (TMC 435350) is a potent inhibitor of HCV NS3/4A protease (Ki = 0.36 nM) and viral replication (replicon EC50 = 7.8 nM). |
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