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Combretastatin A4 Phosphate (CA4P) Disodium Salt
Product Number :
C16282
Product Name :
Combretastatin A4 Phosphate (CA4P) Disodium Salt
CAS No. :
168555-66-6
Synonyms :
Fosbretabulin Disodium
Chemical Name :
Molecular Formula :
C18H19O8P.2Na
Molecular Weight :
440.29
Molecular Structure :
Appearance :
Specification :
Application :
Registration :
Storage Condition :

Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium is the water-soluble prodrug of Combretastatin A4 (CA4), which is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM in a cell-free assay. Fosbretabulin Disodium inhibits the polymerization of tubulin with IC50 of 2.4 μM, and also disrupts tumor vasculature. Phase 3.

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