产品编号 : |
C12460 |
产品名称 : |
EGCG |
中文名 : |
(-)-表没食子儿茶素没食子酸酯 |
CAS No. : |
989-51-5 |
别名 : |
(-)-Epigallocatechin Gallate |
化学名称 : |
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分子式 : |
C22H18O11 |
分子量 : |
458.37 |
结构式 : |
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外观 : |
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纯度 : |
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应用 : |
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Registration : |
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Storage Condition : |
Biological Activity: β-secretase (BACE1) inhibitor (IC50 = 1.6 μM); inhibits amyloid assembly. Inhibits the formation of amyloid fibrils by proteins such as Aβ, α-synuclein and huntingtin. Reduces Aβ42-induced cell death in three different cell types. Also inhibits glutamate dehydrogenase. Inhibits cell growth and selectively induces apoptosis in A431 and human pancreatic cancer cells. Also a DNMT1 inhibitor.
声明:
如果该化合物涉及专利保护,请勿作为商业目的使用,且仅供实验分析及研究之目的;如被销售到构成专利侵权的国家,则相应的一切风险将由买方承担。