Product Number :	C10560
Product Name :	Cyclopamine
CAS No. :	4449-51-8
Synonyms :	11-Deoxojervine
Chemical Name :
Molecular Formula :	C27H41NO2
Molecular Weight :	411.62
Molecular Structure :
Appearance :	White crystalline solid
Specification :	In-House Standard
Application :
Registration :
Storage Condition :

Biological Activity: Inhibitor of hedgehog (Hh) signaling, likely via direct inhibition of Smoothened, the accessory protein to the putative Hh receptor Patched. Anticancer and teratogenic in vivo. Depletes stem-like cancer cells in glioblastoma and blocks tumor engraftment. Can also be used to induce differentiation of human embryonic stem cells (hESCs) into hormone-expressing endocrine cells. 

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