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Acadesine(Aicar,NSC 105823)
| Catalogue No. : |
C13253 |
| Product Name: |
Acadesine(Aicar,NSC 105823) |
| Synonym: |
AICAR, AICA-riboside |
| Chemical Name: |
5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside, Acadesine, N1-(β-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide |
| CAS No. : |
2627-69-2 |
| Structure : |
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| Molecular Formula: |
C9H14N4O5 |
| Molecular Weight: |
258.23 |
| Appearance: |
White solid |
| Purity: |
>99% |
| Usage: |
AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle. |
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