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OSI-906(Linsitinib)
| Catalogue No. : |
C13962 |
| Product Name: |
OSI-906(Linsitinib) |
| Chemical Name: |
cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol |
| CAS No. : |
867160-71-2 |
| Structure : |
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| Molecular Formula: |
C26H23N5O |
| Molecular Weight: |
421.49 |
| Purity: |
>99% |
| Usage: |
OSI-906 is a potent, selective orally active inhibitor of the insulin-like growth factor-1 receptor (IGF-1R).OSI-906 demonstrated robust anti-tumor activity in an IGF-1R dependent xenograft model when administered orally once a day at doses of 25 and 75 mg/kg. OSI-906 not only slowed the growth of IGF-1R-dependent tumors, but also reduced proliferation and/or survival of a broad panel of tumor cell lines. |
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