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Cinacalcet HCl(AMG-073 HCl)
| Catalogue No. : |
C13479 |
| Product Name: |
Cinacalcet HCl(AMG-073 HCl) |
| Synonym: |
AMG-073 HCl;Cinacalcet hydrochloride;Mimpara, Sensipar |
| Chemical Name: |
(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride |
| CAS No. : |
364782-34-3 |
| Structure : |
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| Molecular Formula: |
C22H23ClF3N |
| Molecular Weight: |
393.87 |
| Solubility: |
Soluble in Methanol |
| Purity: |
>99% |
| Usage: |
AMG-073 HCl (Cinacalcet hydrochloride) represents a new class of compounds for the treatment of hyperparathyroidism known as calcimimetics, which reduce parathyroid hormone (PTH) synthesis and secretion by increasing the sensitivity of the parathyroid calcium-sensing receptor (CaR) to extracellular calcium. The current study evaluates the efficacy and safety of AMG 073 when added to conventional treatment of secondary hyperparathyroidism in end-stage renal disease (ESRD). |
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