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HA 14-1
| Catalogue No. : |
C13741 |
| Product Name: |
HA 14-1 |
| Synonym: |
HA-14-1;HA 14-1 |
| Chemical Name: |
2-Amino-6-bromo-alpha-cyano-3-(ethoxycarbonyl)-(alphaR,4R)-rel-4H-1-benzopyran-4-acetic acid ethyl ester;Ethyl [2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)]-4H-chromene-3-carboxylate |
| CAS No. : |
65673-63-4 |
| Structure : |
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| Molecular Formula: |
C17H17BrN2O5 |
| Molecular Weight: |
409.23 |
| Purity: |
>98% |
| Usage: |
Cell-permeable inhibitor of Bcl-2 protein (IC50 ~ 9 μM); acts by binding to the surface pocket. Disrupts Bax/Bcl-2 interaction and induces apoptosis of tumor cells. Also binds to the antiapoptotic Blc-2 proteins Bcl-XL and Bcl-w. |
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