|
|
|
 |
| Location: Home -
Products - Reference Compounds&Impurities - Anti-Cancer(Oncology) Agents
|
KU-55933
| Catalogue No. : |
C13790 |
| Product Name: |
KU-55933 |
| Synonym: |
KU 55933;KU55933 |
| Chemical Name: |
2-(4-Morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one;2-Morpholin-4-yl-6-thianthren-1-ylpyran-4-one |
| CAS No. : |
587871-26-9 |
| Structure : |
|
| Molecular Formula: |
C21H17NO3S2 |
| Molecular Weight: |
395.49 |
| Purity: |
>98% |
| Usage: |
Potent, selective and competitive ATM kinase inhibitor (Ki = 2.2 nM, IC50 values are 13, 2500, 9300, 16600, > 100000 and > 100000 nM at ATM, DNA-PK, mTOR, PI 3-kinase, PI 4-K and ATR respectively). Decreases viability of MCF-7, A549 and HCT116 cells and decreases p21CIP1 levels in vitro. Acts as a radio- and chemosensitizer for the treatment of cancer. |
|
| Products protected by valid patents are not offered for sale in countries, where the sale of such products constitutes a patent infringement. As it is impossible for us to be informed about the patent situation in all countries, the liability for patent infringement is exclusively to be understood as buyer's risk. |
|
|
