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Products - Reference Compounds&Impurities - Anti-Cancer(Oncology) Agents
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RITA(NSC-652287)
| Catalogue No. : |
C16330 |
| Product Name: |
RITA(NSC-652287) |
| Synonym: |
NSC 652287;NSC-652287;NSC652287;SOS BISMETHANOL |
| Chemical Name: |
5,5'-(2,5-Furandiyl)bis-2-thiophenemethanol;2,5-bis(5-hydroxymethyl-2-thienyl) Furan;2-Thiophenemethanol, 5,5'-(2,5-furandiyl)bis- |
| CAS No. : |
213261-59-7 |
| Structure : |
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| Molecular Formula: |
C14H12O3S2 |
| Molecular Weight: |
292.37 |
| Purity: |
>98% |
| Usage: |
Anti-tumor agent that binds wild-type p53 (Kd = 1.5 nM) preventing p53-MDM2 (HDM2) interaction. Induces p53 accumulation and stimulates apoptosis in tumor cell lines expressing wild-type p53 in vitro and in vivo. Inhibits HPV-E6-mediated proteasomal degradation. Suppresses expression of cervical carcinoma HeLa xenografts in vivo. |
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