Product Name: L-Biopterin
CAS No. : 22150-76-1
Synonyms: NSC 339699; 6-Biopterin;L-erythro-Biopterin;(1'R,2'S)-Biopterin
Chemical Name: 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]pteridin-4(1H)-one;2-amino-7-(1,2-dihydroxypropyl)pteridin-4(1H)-one
Molecular Formula: C9H11N5O3
Molecular Weight: 237.22
Appearance: Colorless to pale yellow powder
Purity: >98% HPLC
** L-Biopterin is the oxidized form of tetrahydro-L-biopterin (BH4), a nitric oxide synthase (NOS) cofactor. L-Biopterin can be reduced to BH4 via thioredoxin reductase followed by dihydropteridine reductase or reduced glutathione. It is extremely toxic to human melanocytes in culture (IC50 = 0.2 μM after 48 hrs).L-Biopterin is rarely found under physiological conditions except in the epidermis of patients with the depigmentation disorder Vitiligo.
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