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Aristolactam I
Product Number :
CLN10150
Product Name :
Aristolactam I
CAS No. :
13395-02-3
Synonyms :
Aristololactam; Aristololactam I​
Chemical Name :
Molecular Formula :
C17H11NO4
Molecular Weight :
293.28
Molecular Structure :
Appearance :
Specification :
Application :
Registration :
Storage Condition :
2-8℃

1.Aristolactam I against IL-6 (IC50 = 52 ± 8 μM) and TNFα (IC50 =116.8 ± 83.25 μM), respectively.
2.Aristolactam showed higher nephrotoxicity than aristolochic acid, which might be attributable to the differences in their inhibition of AQP1.
3.Aristolactam I possesses strong in vitro antimycobacterial activity against Mycobacterium tuberculosis H37Rv with MIC values ranging between 12.5 and 25 μg/mL.

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